I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals. The details of the IRB/oversight body that provided approval or exemption for the research described are given below:Įthics Committee for Research of Clinica Eugin gave ethical approval of this work (approval code: ALGO2) on the 20th of October of 2020. I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. Nuria Correa is a PhD Student of the doctoral program in Computer Science at the Universitat Autonoma de Barcelona. Ministry of Science and Innovation, by EUROVA Innovative Training Network (MSCA- ITN-2019-860960), and by intramural funding by Clinica Eugin-Eugin Group. This work was supported by Doctorat Industrial funded by Generalitat de Catalunya, by project CI-SUSTAIN funded by the Spanish The authors have declared no competing interest. Conclusions This methodology constitutes a simple but effective method to bridge the gap between current clinical dosing policies and gold policies based on the true underlying and often unknown dose-response functions.
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